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Bedfordshire and Luton Joint Formulary
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Bedfordshire CCG
Luton & Dunstable University Hospital NHS Foundation Trust
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 Formulary Chapter 5: Infections - Full Chapter
Notes:

When a bacterial pathogen is isolated from a clinical specimen and sensitivities are known, treatment should be adjusted to use the narrowest-spectrum antibiotic.The oral route of administration will be appropriate either on initiation or after 2 to 3 days of intravenous therapy. Certain infections e.g. severe sepsis, bacterial meningitis and neutropenic sepsis require intravenous antibiotics for the full period of treatment. All intravenous therapy should be reviewed at 48 hours (ideally daily). A switch from IV to oral therapy should be considered as soon as it is clinically appropriate with the exception of patients with osteomyelitis, necrotising fasciitis, septic arthritis and infections mentioned above. Initially when the infecting organism or the source of infection is unknown, 'broad-spectrum' antibiotics are appropriate. Once clarified (laboratory results), therapy should be altered to a 'narrow spectrum' agent to help minimise the risk of development of antimicrobial resistance. REFER TO TRUST/COMMUNITY ANTIMICROBIAL GUIDELINES , or the Antimicrobial Microguide app.

Any drug not listed on the Formulary should be considered Non-Formulary - Not recommended for prescribing

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 Details...
05.01.01.03  Expand sub section  Broad-spectrum penicillins
Amoxicillin
(Oral)
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Formulary
Green
250mg & 500mg Capsules
125mg/5mL & 250mg/5mL sugar free syrup
3g sugar free Sachets

Amoxicillin has good oral bioavailability. The switch from IV to oral amoxicillin should take place as soon as a patientís clinical condition improves.  
   
Amoxicillin
(Injection)
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Formulary
Red
250mg & 500mg Injection

Amoxicillin has good oral bioavailability. The switch from IV to oral amoxicillin should take place as soon as a patientís clinical condition improves.  
   
Co-Amoxiclav
(Oral)
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Formulary
Green
125/31.25mg in 5mL Sugar free Suspension
250/62.5mg in 5mL Sugar free Suspension
250/125mg & 500/125mg Tablets

Amoxicillin and clavulanate have good oral bioavailability. The switch from IV to oral should take place as soon as a patientís clinical condition improves. 
Link  Alternatives to co-amoxiclav
   
Co-Amoxiclav 400mg/57mg (Augmentin-Duoģ)
(Suspension)
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Restricted Drug Restricted
Green
Paediatrics only. Only to be prescribed when three times daily dosing is a problem. 
   
Co-Amoxiclav
(Injection)
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Formulary
Red
600mg & 1.2g Injection

Amoxicillin and clavulanate have good oral bioavailability. The switch from IV to oral should take place as soon as a patientís clinical condition improves.  
Link  Alternatives to co-amoxiclav
   
 ....
 Non Formulary Items
Ampicillin

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Non Formulary
 
Ampicillin  (Penbritin®)

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Non Formulary
 
Co-Fluampicil

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Non Formulary
 
Co-Fluampicil  (Magnapen®)

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
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Link to adult BNF
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Link to children's BNF
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Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Red

RED - Hospital only Ė to be prescribed by a specialist and supplied from secondary care ONLY throughout treatment  

Amber

Amber medicines are considered suitable for GP prescribing following specialist initiation.  

Green

These medicines are appropriate for initiation in both primary and secondary care. Prescribing is appropriate within licensed or local recommendations   

Amber SCG

Shared Care - these medicines require specialist initiation and stabilisation. Ongoing division of responsibility for drug and disease monitoring between specialist and GP by a Shared Care Guideline (SCG). If no SCG in place status reverts to red.   

Black

A decision has been made by either or both the local or national NHS not to routinely commission this preparation for its licensed indications. Do not prescribe.   

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