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Bedfordshire and Luton Joint Formulary
Bedford Hospital NHS Trust
Bedfordshire CCG
Luton & Dunstable University Hospital NHS Foundation Trust
Luton CCG
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 Formulary Chapter 8: Malignant disease and immunosuppression - Full Chapter
Notes:

Any drug not listed on the Formulary should be considered Non-Formulary - Not recommended for prescribing

 Details...
08.03.04.02  Expand sub section  Prostate cancer and gonadorelin analogues
08.03.04.02  Expand sub section  Gonadorelin analogues
08.03.04.02  Expand sub section  Anti-androgens
Abiraterone 250mg (Zytiga)
(Tablets)
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Formulary
Red
High Cost Medicine
Cancer Drugs Fund

FOR ALL PRESCRIBING – Blueteq or High cost drug form required – see link from Formulary homepage.

Approved in accordance with NICE TA259 & TA387 for the treatment of metastatic prostate cancer.

 
Link  MHRA Drug Safety Update (Dec 2017): Radium-223 dichloride (Xofigo▼): do not use in combination with abiraterone and prednisone/prednisolone, following clinical trial signal of increased risk of death and fractures
Link  NICE TA259: Abiraterone for castration resistant prostate cancer
Link  NICE TA387: Abiraterone for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicated
   
Bicalutamide
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Formulary
Amber

50mg & 150mg Tablets

 
   
Buserelin
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Formulary
Red

5.5mg/5.5mL Injection

 
   
Cyproterone
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Formulary
Green

50mg Tablets

 
   
Enzalutamide 40mg (Xtandi)
(Capsules)
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Formulary
Red
High Cost Medicine

FOR ALL PRESCRIBING – Blueteq or High cost drug form required – see link from Formulary homepage.

Approved in accordance with NICE TA377 and TA316 for the treatment of hormone-relapsed prostate cancer.

 
Link  NICE TA316: Enzalutamide for metastatic hormone‑relapsed prostate cancer previously treated with a docetaxel‑containing regimen
Link  NICE TA377: Enzalutamide for treating metastatic hormone-relapsed prostate cancer before chemotherapy is indicated
   
Flutamide
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Formulary
Amber

250mg Tablets

 
   
Goserelin
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Formulary
Amber

3.6mg Injection

by sub-cutaneous injection every 28 days.

 
   
 ....
 Non Formulary Items
Flutamide  (Drogenil®)

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Non Formulary
 
Goserelin  (Zoladex LA)
(10.8mg)

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Non Formulary
 
Leuprorelin Acetate  (Prostap 3)

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Non Formulary
 
Leuprorelin Acetate  (Prostap SR)

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Non Formulary
 
Triptorelin  (Decapeptyl)

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Non Formulary
 
Triptorelin  (Gonapeptyl Depot)

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Red

RED - Hospital only to be prescribed by a specialist and supplied from secondary care ONLY throughout treatment  

Amber

Amber medicines are considered suitable for GP prescribing following specialist initiation.  

Green

These medicines are appropriate for initiation in both primary and secondary care. Prescribing is appropriate within licensed or local recommendations   

Amber SCG

Shared Care - these medicines require specialist initiation and stabilisation. Ongoing division of responsibility for drug and disease monitoring between specialist and GP by a Shared Care Guideline (SCG). If no SCG in place status reverts to red.   

Black

A decision has been made by either or both the local or national NHS not to routinely commission this preparation for its licensed indications. Do not prescribe.   

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